Here are a few suggestions for your next trip from Issoire

In 4 hours, you can reach Paris, Lyon.

In 5 hours, you can reach Marseille.

In 6 hours, you can reach Genève, Lausanne, Toulouse, Montpellier, Reims.

In 7 hours, you can reach Brussels, Basel, Anderlecht, Nantes, Schaerbeek, Strasbourg, Bordeaux, Rouen, Lille, Molenbeek-Saint-Jean...

In 8 hours, you can reach London, Zürich, Luxembourg, Milan, Antwerpen, Esch-sur-Alzette, Dudelange, Gent.