Here are a few suggestions for your next trip from Ancona

In 2 hours, you can reach Bologna, Rimini, Forlì, Cesena, Marotta-Mondolfo, Pesaro, Potenza Picena-Montelupone, Fano(I), Montecarotto-Castelbellino, Porto S.Giorgo-Fermo...

In 3 hours, you can reach Parma, Modena, Reggio nell'Emilia, Pescara, Terni, Porto d'Ascoli, Trevi, Cerreto d'Esi, Scafa-S. Valentino-Caramanico Terme, Orte...

In 4 hours, you can reach Rome, Milan, Verona, Padova, Mestre, Foggia, Piacenza, Barletta, Silvi, Roseto degli Abruzzi...

In 5 hours, you can reach Bari, Ferrara, Bolzano, Rovigo, Fidenza, Gioia del Colle, Rimini Miramare, Rovereto, Imola, Trani...

In 6 hours, you can reach Taranto, Alessandria, Mezzocorona, Ora/Auer, Castel S. Pietro Terme, Milano Rogoredo, Martinsicuro, Fortezza/Franzensfeste, Tarvisio Boscoverde, Fasano...

In 7 hours, you can reach Turin, Villach, Trento, Arezzo, Francavilla Fontana, Brennero/Brenner, Fiorenzuola, Torino Lingotto.

In 8 hours, you can reach Klagenfurt am Wörthersee.

In 9 hours, you can reach Innsbruck, Schwarzach-St.Veit.

In 10+ hours, you can reach Vienna, Munich, Salzburg, Florence, Wiener Neustadt, Prato, Kufstein, Wörgl Hbf, Jenbach Zillertalbahn, Jenbach...