Here are a few suggestions for your next trip from Rheine-Mesum

In 2 hours, you can reach Enschede, Düsseldorf, Essen, Dortmund, Bremen.

In 3 hours, you can reach Amsterdam, Hamburg, Köln, Utrecht, Almere Stad, Nijmegen, Arnhem.

In 4 hours, you can reach Berlin, Rotterdam, Haga, Groningen, Liège, Frankfurt pe Main, Eindhoven, Tilburg, Breda, Haarlem...

In 5 hours, you can reach Bruxelles, Anvers, Anderlecht, Stuttgart, Schaerbeek, Namur, Leuven.